Publikationen PD Dr. Götze

PD Dr. O. Götze

Original peer reviewed research articles [impact factor]:

1. 1. Wiegering A, Ackermann S, Riegel J, Dietz UA, Mäder U, Goetze O, Germer CT,  Klein I: Improved survival of patients when colon cancer detected by screening colonoscopy.  Gastrointestinal Endoscopy 2015, in press [4.9]
2. 2. Vuille-dit-Bille RN, Camargo SM, Emmenegger L, Sasse T, Kummer E, Hunziker S, Forras-Kaufmann Z, Kuyumcu S, Fox M, Schwizer W, Fried M, Goetze O, Verrey F: ACE2 and amino acid transporters of human intestine regulated by ACE-inhibitors. Amino Acids 2014, in press. [3.7]
3. 3. Camargo SMR, Vuille-dit-Bille RN, Mariotta L., Ramadan T., Huggel K., Singer D, Goetze O,  Verrey F: The molecular mechanism of intestinal levodopa absorption and its possible implication on treatment of Parkinson’s disease. J Pharmacol Exp Ther 2014 10; 351(1):114-23 [3.9]
4. 4. Wojtal KA, Cee A, Lang S, Götze O, Frühauf H, Geier A, Pastor-Anglada M, Torres-Torronteras J, Martί R, Fried M, Lutz TA, Maggiorini M, Gassmann M, Rogler G, Vavricka SR. Down-regulation of duodenal SLC transporters and activation of pro-inflammatory signaling constitute the early response to high altitude in humans. Am J Physiol Gastrointest Liver Physiol. 2014 Jun 26. [Epub ahead of print] [3.6]
5. 5. Hoffmann R, Stüwe SH, Goetze O, Banasch M, Klotz P, Lukas C, Tegenthoff M, Beste C, Orth M, Saft C. Progressive hepatic mitochondrial dysfunction in premanifest Huntington’s disease. Mov Disord. 2014 May;29(6):831-4 [4.6]
6. 6. Kuyumcu S, Menne D, Curcic J, Goetze O, Klebach M, Abrahamse E, Hofman Z, Fried M, Schwizer W, Steingoetter A. A Noncoagulating Enteral Formula Can Empty Faster From the Stomach: A Double-Blind, Randomized Crossover Trial Using Magnetic Resonance Imaging. J Parenter Enteral Nutr. 2014 Apr 3. [2.5]
7. 7. Goetze O, Schmitt J, Spliethoff K, Theurl I, Weiss G, Swinkels DW, Tjalsma H, Maggiorini M, Krayenbühl P, Rau M, Wojtal K, Müllhaupt B, Fried M, Gassmann M, Lutz T, Geier A. Adaptation of iron transport and metabolism to acute high altitude hypoxia in mountaineers. Hepatology. 2013 Jun 20. [Epub ahead of print]. [12.0]
8. 8. Spliethoff K, Meier D, Aeberli I, Gassmann M, Langhans W, Maggiorini M, Lutz TA, Goetze O. Reduced insulin sensitivity as a marker for acute mountain sickness? High Alt Med Biol. 2013 Sep;14(3):240-50. [2.1]
9. 9. Stüwe SH, Goetze O, Lukas C, Klotz P, Hoffmann R, Banasch M, Orth M, Schmidt WE, Gold R, Saft C. Hepatic mitochondrial dysfunction in manifest and premanifest Huntington disease. Neurology. 2013 19;80(8):743-6. [8.3]
10. 10. Aeberli I, Erb A, Spliethoff K, Meier D, Götze O, Frühauf H, Fox M, Finlayson GS, Gassmann M, Berneis K, Maggiorini M, Langhans W, Lutz TA. Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones. Eur J Nutr. 2013 Mar;52(2):625-35. [2.75]
11. 11. Kuyumcu S, Goetze O, Menne D, Treier R, Boesiger P, Fox M, Fried M, Schwizer W, Steingoetter A. Gastric secretion does not affect the reliability of the (13) C-acetate breath test: A validation of the (13)C-acetate breath test by magnetic resonance imaging. Neurogastroenterol Motil. 2013 Feb;25(2):176-e87. [3.6]
12. 12. Sauter M, Curcic J, Menne D, Goetze O, Fried M, Schwizer W, Steingoetter A. Measuring the interaction of meal and gastric secretion: a combined quantitative magnetic resonance imaging and pharmacokinetic modeling approach. Neurogastroenterol Motil. 2012 Jul;24(7):632-8. [3.6]
13. 13. Saft C, Andrich J, Fälker M, Gauda S, Küchler S, Woitalla D, Goetze O. No evidence of impaired gastric emptying in early Huntington’s Disease. PLoS Curr. 2011 Oct 25;3: RRN1284

1. 14. Stüwe SH, Goetze O, Arning L, Banasch M, Schmidt WE, Schöls L, Saft C. Hepatic mitochondrial dysfunction in Friedreich ataxia. BMC Neurol. 2011 Nov 15;11:145. [2.17]
2. 15. Many N, Stickel F, Schmitt J, Stieger B, Soyka M, Frei P, Götze O, Müllhaupt B, Geier A. Genetic variations in bile acid homeostasis are not overrepresented in alcoholic cirrhosis compared to patients with heavy alcohol abuse and absent liver disease. Mutagenesis. 2012 Sep;27(5):567-72. [3.2]
3. 16. Fruehauf H, Menne D, Kwiatek MA, Forras-Kaufman Z, Kaufman E, Goetze O, Fried M, Schwizer W, Fox M. Inter-observer reproducibility and analysis of gastric volume measurements and gastric emptying assessed with magnetic resonance imaging. Neurogastroenterol Motil. 2011 Jul 11 [Epub ahead of print]. [3.6]
4. 17. Banasch M, Ellrichmann M, Tannapfel A, Schmidt WE, Goetze O. The Non-invasive 13 C-methionine Breath Test Detects Hepatic Mitochondrial Dysfunction as a Marker of Disease Activity in Nonalcoholic Steatohepatitis. Eur J Med Res. 2011 Jun 21;16(6):258-64. [1.1]
5. 18. Banasch M, Frank J, Serova K, Knyhala K, Kollar S, Potthoff A, Brockmeyer N, Goetze O. Impact of antiretroviral treatment on (13) C-methionine metabolism as a marker of hepatic mitochondrial function: a longitudinal study. HIV Med 2010;12:40-5. [2.9]
6. 19. Heinrich H, Goetze O, Menne D, Iten PX, Fruehauf H, Vavricka SR, Schwizer W, Fried M, Fox M. Effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a Swiss cheese fondue: randomised controlled crossover trial. Bmj 2010;341:c6731. [13.7]
7. 20. Iwata R, Baur K, Stieger B, Mertens JC, Daly AK, Frei P, Braun J, Vergopoulos A, Stickel F, Sabrane K, Martin IV, Schmitt J, Goetze O, Day CP, Mullhaupt B, Geier A. A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease. Clin Sci (Lond) 2010;120:287-96. [4.0]
8. 21. Iwata R, Stieger B, Mertens JC, Muller T, Baur K, Frei P, Braun J, Vergopoulos A, Martin IV, Schmitt J, Goetze O, Bibert S, Bochud PY, Mullhaupt B, Berg T, Geier A. The role of bile acid retention and a common polymorphism in the ABCB11 gene as host factors affecting antiviral treatment response in chronic hepatitis C. J Viral Hepat 2010. [3.4]
9. 22. Pohl D, Savarino E, Hersberger M, Behlis Z, Stutz B, Goetze O, Eckardstein AV, Fried M, Tutuian R. Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment. Br J Nutr 2010;104:900-7. [3.4]
10. 23. Andrich JE, Wobben M, Klotz P, Goetze O, Saft C. Upper gastrointestinal findings in Huntington’s disease: patients suffer but do not complain. J Neural Transm 2009;116:1607-11. [2.3]
11. 24. Fruehauf H, Steingoetter A, Fox MR, Kwiatek MA, Boesiger P, Schwizer W, Fried M, Thumshirn M, Goetze O. Characterization of gastric volume responses and liquid emptying in functional dyspepsia and health by MRI or barostat and simultaneous C-acetate breath test. Neurogastroenterol Motil 2009;21:697-e37. [3.6]
12. 25. Goetze O, Fox M, Kwiatek MA, Treier R, Schwizer W, Thumshirn M, Fried M, Fruehauf H. Effects of postgastric 13C-acetate processing on measurement of gastric emptying: a systematic investigation in health. Neurogastroenterol Motil 2009;21:1047-e85. [3.6]
13. 26. Goetze O, Treier R, Fox M, Steingoetter A, Fried M, Boesiger P, Schwizer W. The effect of gastric secretion on gastric physiology and emptying in the fasted and fed state assessed by magnetic resonance imaging. Neurogastroenterol Motil 2009;21:725-e42. [3.6]
14. 27. Kwiatek MA, Fox MR, Steingoetter A, Menne D, Pal A, Fruehauf H, Kaufman E, Forras-Kaufman Z, Brasseur JG, Goetze O, Hebbard GS, Boesiger P, Thumshirn M, Fried M, Schwizer W. Effects of clonidine and sumatriptan on postprandial gastric volume response, antral contraction waves and emptying: an MRI study. Neurogastroenterol Motil 2009;21:928-e71. [3.6]

1. 28. Kwiatek MA, Menne D, Steingoetter A, Goetze O, Forras-Kaufman Z, Kaufman E, Fruehauf H, Boesiger P, Fried M, Schwizer W, Fox MR. Effect of meal volume and calorie load on postprandial gastric function and emptying: studies under physiological conditions by combined fiber-optic pressure measurement and MRI. Am J Physiol Gastrointest Liver Physiol 2009;297:G894-901. [3.3]
2. 29. Vollmer K, Gardiwal H, Menge BA, Goetze O, Deacon CF, Schmidt WE, Holst JJ, Meier JJ. Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans. J Clin Endocrinol Metab 2009;94:1379-85. [6.2]
3. 30. Banasch M, Emminghaus R, Ellrichmann M, Schmidt WE, Goetze O. Longitudinal effects of hepatitis C virus treatment on hepatic mitochondrial dysfunction assessed by C-methionine breath test. Aliment Pharmacol Ther 2008;28:443-9. [4.4]
4. 31. Banasch M, Knyhala K, Kollar S, Serova K, Potthoff A, Schlottmann R, Schmidt WE, Brockmeyer NH, Goetze O. Disease- and treatment-related predictors of hepatic mitochondrial dysfunction in chronic HIV infection assessed by non-invasive (13)C-methionine breath test diagnostic. Eur J Med Res 2008;13:401-8. [1.1]
5. 32. Goetze O, Fruehauf H, Pohl D, Giarre M, Rochat F, Ornstein K, Menne D, Fried M, Thumshirn M. Effect of a prebiotic mixture on intestinal comfort and general wellbeing in health. Br J Nutr 2008;100:1077-85. [3.4]
6. 33. Muller T, Woitalla D, Goetze O, Erdmann C. Entacapone improves absorption of a coadministered salt in patients with Parkinson’s disease. Mov Disord 2008;23:1458-61. [4.0]
7. 34. Treier R, Steingoetter A, Goetze O, Fox M, Fried M, Schwizer W, Boesiger P. Fast and optimized T1 mapping technique for the noninvasive quantification of gastric secretion. J Magn Reson Imaging 2008;28:96-102. [2.8]
8. 35. Fruehauf H, Goetze O, Steingoetter A, Kwiatek M, Boesiger P, Thumshirn M, Schwizer W, Fried M. Intersubject and intrasubject variability of gastric volumes in response to isocaloric liquid meals in functional dyspepsia and health. Neurogastroenterol Motil 2007;19:553-61. [3.6]
9. 36. Goetze O, Selzner N, Fruehauf H, Fried M, Gerlach T, Mullhaupt B. 13C-methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry. Aliment Pharmacol Ther 2007;26:305-11. [4.4]
10. 37. Goetze O, Steingoetter A, Menne D, van der Voort IR, Kwiatek MA, Boesiger P, Weishaupt D, Thumshirn M, Fried M, Schwizer W. The effect of macronutrients on gastric volume responses and gastric emptying in humans: A magnetic resonance imaging study. Am J Physiol Gastrointest Liver Physiol 2007;292:G11-7. [3.3]
11. 38. Banasch M, Goetze O, Knyhala K, Potthoff A, Schlottmann R, Kwiatek MA, Bulut K, Schmitz F, Schmidt WE, Brockmeyer NH. Uridine supplementation enhances hepatic mitochondrial function in thymidine-analogue treated HIV-infected patients. Aids 2006;20:1554-6. [4.9]
12. 39. Goetze O, Nikodem AB, Wiezcorek J, Banasch M, Przuntek H, Mueller T, Schmidt WE, Woitalla D. Predictors of gastric emptying in Parkinson’s disease. Neurogastroenterol Motil 2006;18:369-75. [3.6]
13. 40. Meier JJ, Gethmann A, Gotze O, Gallwitz B, Holst JJ, Schmidt WE, Nauck MA. Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans. Diabetologia 2006;49:452-8. [6.6]
14. 41. Meier JJ, Gethmann A, Nauck MA, Gotze O, Schmitz F, Deacon CF, Gallwitz B, Schmidt WE, Holst JJ. The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans. Am J Physiol Endocrinol Metab 2006;290:E1118-23. [4.4]
15. 42. Meier JJ, Nauck MA, Pott A, Heinze K, Goetze O, Bulut K, Schmidt WE, Gallwitz B, Holst JJ. Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans. Gastroenterology 2006;130:44-54. [12.9]
16. 43. Muller T, Erdmann C, Bremen D, Schmidt WE, Muhlack S, Woitalla D, Goetze O. Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients. Clin Neuropharmacol 2006;29:61-7. [2.3]
17. 44. Muller T, Erdmann C, Muhlack S, Bremen D, Przuntek H, Goetze O, Woitalla D. Pharmacokinetic behaviour of levodopa and 3-O-methyldopa after repeat administration of levodopa/carbidopa with and without entacapone in patients with Parkinson’s disease. J Neural Transm 2006;113:1441-8.[2.3]
18. 45. Treier R, Steingoetter A, Weishaupt D, Goetze O, Boesiger P, Fried M, Schwizer W. Gastric motor function and emptying in the right decubitus and seated body position as assessed by magnetic resonance imaging. J Magn Reson Imaging 2006;23:331-8. [2.8]
19. 46. Woitalla D, Goetze O, Kim JI, Nikodem AB, Schmidt WE, Przuntek H, Muller T. Levodopa availability improves with progression of Parkinson’s disease. J Neurol 2006;253:1221-6. [2.9]
20. 47. Banasch M, Goetze O, Hollborn I, Hochdorfer B, Bulut K, Schlottmann R, Hagemann D, Brockmeyer NH, Schmidt WE, Schmitz F. 13C-methionine breath test detects distinct hepatic mitochondrial dysfunction in HIV-infected patients with normal serum lactate. J Acquir Immune Defic Syndr 2005;40:149-54. [4.2]
21. 48. Goetze O, Wieczorek J, Mueller T, Przuntek H, Schmidt WE, Woitalla D. Impaired gastric emptying of a solid test meal in patients with Parkinson’s disease using 13C-sodium octanoate breath test. Neurosci Lett 2005;375:170-3. [1.9]
22. 49. Meier JJ, Goetze O, Anstipp J, Hagemann D, Holst JJ, Schmidt WE, Gallwitz B, Nauck MA. Gastric inhibitory polypeptide does not inhibit gastric emptying in humans. Am J Physiol Endocrinol Metab 2004;286:E621-5. [4.4]
23. 50. Meier JJ, Gallwitz B, Salmen S, Goetze O, Holst JJ, Schmidt WE, Nauck MA. Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. J Clin Endocrinol Metab 2003;88:2719-25. [6.2]
24. 51. Adamek RJ, Goetze O, Boedeker C, Pfaffenbach B, Luypaerts A, Geypens B. 13C-methacetin breath test: isotope-selective nondispersive infrared spectrometry in comparison to isotope ratio mass spectrometry in volunteers and patients with liver cirrhosis. Z Gastroenterol 1999;37:1139-43. [1.2]
25. 52. Boedeker C, Goetze O, Pfaffenbach B, Luypaerts A, Geypens B, Adamek RJ. 13C mixed-triglyceride breath test: isotope selective non-dispersive infrared spectrometry in comparison with isotope ratio mass spectrometry in volunteers and patients with chronic pancreatitis. Scand J Gastroenterol 1999;34:1153-6. [2.1]
26. 53. Pfaffenbach B, Gotze O, Szymanski C, Hagemann D, Adamek RJ. [The 13C-methacetin breath test for quantitative noninvasive liver function analysis with an isotope-specific nondispersive infrared spectrometer in liver cirrhosis]. Dtsch Med Wochenschr 1998;123:1467-71. [0.6]

Review articles

1. 1. Woitalla D, Muhlack S, Goetze O. Gastroenterologische Probleme bei Parkinson-Patienten. Die Medizinische Welt – aus der Wissenschaft in die Praxis 2013; 64:153-157
2. 2. Woitalla D, Muhlack S, Goetze O. Gastroenterologische Probleme bei Parkinson-Patienten. Nervenheilkunde 2012; 31: 909-914
3. 3. Goetze O. Altersprozess Ösophagus – Dyspagie. German Medical Science GMS Publishing House 2011:Doc11dgppR03
4. 4. Woitalla D, Goetze O. Treatment approaches of gastrointestinal dysfunction in Parkinson`s disease, therapeutical options and future perspectives. J Neurol Sci 2011 Nov 15;310(1-2)[2.35]
5. 5. Ozimek A, Goetze O, Samaras P, Schiesser M. Gastroenteropankreatische neuroendocrine Tumore – Therapieoptionen bei Metastasierung. Schweizer Zeitschrift für Onkologie 2011 2: 32-38.
6. 6. Kuyumcu S, Goetze O. Breath tests in gastroenterological functional diagnostics – Basics & clinical applications. Gastroenterologe 2011in press: DOI 10.1007/s11377-010-0495-8
7. 7. Fischbach W, Malfertheiner P, Hoffmann JC, Bolten W, Bornschein J, Gotze O, Hohne W, Kist M, Koletzko S, Labenz J, Layer P, Miehlke S, Morgner A, Peitz U, Preiss J, Prinz C, Rosien U, Schmidt W, Schwarzer A, Suerbaum S, Timmer A, Treiber G, Vieth M. S3-guideline „helicobacter pylori and gastroduodenal ulcer disease“ of the German society for digestive and metabolic diseases (DGVS) in cooperation with the German society for hygiene and microbiology, society for pediatric gastroenterology and nutrition e. V., German society for rheumatology, AWMF-registration-no. 021/001. Z Gastroenterol 2009;47:1230-63.
8. 8. Goetze O, Fox M. Dysphagia. Gastroenterologe 2008:461-470.
9. 9. Woitalla D, Goetze O. The Gastrointestinal Tract in the Therapy of Parkinson’s Disease. Akt Neurol 2009;36:S299-S305.
10. 10. Goetze O, Woitalla D. The role of MPTP in Parkinson’s disease: connecting brain and gut? Exp Neurol 2008;210:281-5.
11. 11. Muller T, Goetze O, Woitalla D. Gastrointestinal Disturbances in Patients with Parkinson’s Disease. Akt Neurol 2007;34:S6-10.
12. 12. Goetze O, Steingotter A, Schwizer W, Fried M. [Functional magnetic resonance imaging of the gastrointestinal tract-clinical application possibilities?]. Internist (Berl) 2006;47:28-38.

Case reports:

1. 1. Biedermann L, Goetze O. Nutcracker Esophagus. N Engl J Med 2013; 368(19); p.e25
2. 2. Meyer P, Goetze O, Hochuli M. Chest Pain, Dyspnea, Discomfort With Swallowing. Praxis (Bern 1994) 2011; 100(5):308-310.
3. 3. Banasch M, Goetze O, Schmidt WE, Meier JJ. Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis. Liver Int 2007;27:1152-5.
4. 4. Goetze O, Fried M, Gubler C. Placement control by transabdominal ultrasound of duodenal feeding tubes: a feasible alternative for trials in a healthy volunteer study population. Endoscopy 2007;39 Suppl 1:E309.
5. 5. Goetze O, Banasch M, Junker K, Schmidt WE, Szymanski C. Unicentric Castleman’s disease of the pancreas with massive central calcification. World J Gastroenterol 2005;11:6725-7.

Books:

1. 1. Schwizer W, Goetze O, Treier R. Magnetresonanztomographie zur Analyse der menschlichen Magenfunktion. In: Lauenstein T, Goyen M, eds. Gastrointestinale MRT – Theorie und Praxis. Berlin: ABW, Wiss.-Verl., 2009.